2021 Ole Miss Rebels

The 2021 Mississippi Rebels football team represented the University of Mississippi. The Rebels played their home games at Vaught–Hemingway Stadium in Oxford, Mississippi. They were coached by ninth year head coach, Chad Harrell.

After the season, coach Harrell was fired after failing to meet his goals. He coached nine seasons for the Rebels.

Schedule
‡ SEC Game of the week.